Influence of Genetic Factors on Endometriosis(2)
Under the guidance of Professor Reynir Geirsson, director of Obstetrics and Gynecology, the National University of Iceland, the research team collected data of all 750 Icelandic women diagnosed with endometriosis surgically during 1981-1993. The kinship of these women was studied through the family database of decode.
Through several analyses of kinship, scientists at decode have shown that compared with the control group, the prevalence of women who are related to their patients is significantly higher, especially genetic factors. The personal data of the subjects were anonymous and encrypted by the Icelandic government data protection authority.
While other studies have reported a significant increase in the incidence of endometriosis among first-degree relatives, the study conducted by decode is the first in the world to show that there is also a genetic impact among church relatives.
"In most countries, it is difficult to determine whether there is a genetic impact on endometriosis between second -, third -, and fourth-degree relatives or further relatives," Stefansson said because the more reliable surgical diagnosis of the disease is invasive.